N-(4-AMINOPHENYL)MALEIMIDE

  • Name: N-(4-AMINOPHENYL)MALEIMIDE
  • CAS: 29753-26-2
  • Purity: 99%
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Details

Factory Export Top Purity N-(4-AMINOPHENYL)MALEIMIDE 29753-26-2 In Stock

  • Molecular Formula: C10H8N2O2
  • Molecular Weight: 188.186
  • Vapor Pressure: 1.22E-06mmHg at 25°C 
  • Melting Point: 173 °C 
  • Refractive Index: 1.688 
  • Boiling Point: 401 °C at 760 mmHg 
  • PKA: 3.70±0.10(Predicted) 
  • Flash Point: 196.3 °C 
  • PSA： 63.40000 
  • Density: 1.419 g/cm3 
  • LogP: 1.34440 

N-(4-AMINOPHENYL)MALEIMIDE(Cas 29753-26-2) Usage

General Description

N-(4-aminophenyl)maleimide is a chemical compound that belongs to the class of maleimide derivatives. It is a white to slightly yellow solid with a melting point of 180-182 degrees Celsius. N-(4-AMINOPHENYL)MALEIMIDE is commonly used in various chemical reactions, such as the synthesis of fluorescent labels, dyes, and pharmaceuticals. As a maleimide derivative, it can readily undergo Michael addition reactions with thiols and other nucleophiles, making it a valuable building block in organic synthesis. It is also used as a probe for the detection of sulfhydryl groups in proteins and other biomolecules, making it a useful tool in biochemical and biomedical research.

InChI:InChI=1/C10H8N2O2/c11-7-1-3-8(4-2-7)12-9(13)5-6-10(12)14/h1-6H,11H2

29753-26-2 Relevant articles

Binding of filamentous actin and winding into fibrillar aggregates by the polyphenolic C-glucosidic ellagitannin vescalagin

Quideau, Stephane,Douat-Casassus, Celine,Delannoy Lopez, Daniela Melanie,Di Primo, Carmelo,Chassaing, Stefan,Jacquet, Remi,Saltel, Frederic,Genot, Elisabeth

, p. 5099 - 5104 (2011)

Winding it up: The plant polyphenolic me...

Microwave-Assisted Synthesis of N-Substituted Maleimide Derivatives as Exogenous Antioxidant Agents

Rammohan, Aluru,Mallikarjuna Reddy, Guda,Raul Garcia, Jarem,Zyryanov, Grigory V.,Sravya, Gundala,Bakthavatchala Reddy, Nemallapudi,Yuvaraja, Gutha

, p. 470 - 476 (2019)

A series of N-substituted maleimide deri...

Design, synthesis and biochemical evaluation of novel ethanoanthracenes and related compounds to target burkitt’s lymphoma

Byrne, Andrew J.,Bright, Sandra A.,McKeown, James P.,O’brien, John E.,Twamley, Brendan,Fayne, Darren,Williams, D. Clive,Meegan, Mary J.

, (2020/01/31)

Lymphomas (cancers of the lymphatic syst...

Production method of maleimide biphenol-type benzoxazine monomer

-

Paragraph 0050-0051; 0054-0055; 0058-0059; 0062-0063; 0066-, (2020/01/12)

The invention provides a production meth...

Chemoselective Hydrogenation of Nitroarenes Catalyzed by Molybdenum Sulphide Clusters

Pedrajas, Elena,Sorribes, Iván,Gushchin, Artem L.,Laricheva, Yuliya A.,Junge, Kathrin,Beller, Matthias,Llusar, Rosa

, p. 1128 - 1134 (2017/03/27)

Herein, we describe an atom efficient an...

29753-26-2 Process route

C<sub>40</sub>H<sub>32</sub>N<sub>4</sub>O<sub>8</sub>
741270-61-1

C40 H32 N4 O8

diethylstilbestrol
56-53-1,8053-00-7

diethylstilbestrol

1‐(4‐aminophenyl)‐1H‐pyrrole‐2,5‐dione
29753-26-2

1‐(4‐aminophenyl)‐1H‐pyrrole‐2,5‐dione

Conditions
Conditions Yield
With water; In dimethylsulfoxide-d6; at 110 ℃;
N-(4-nitrophenyl)maleimide
4338-06-1

N-(4-nitrophenyl)maleimide

1‐(4‐aminophenyl)‐1H‐pyrrole‐2,5‐dione
29753-26-2

1‐(4‐aminophenyl)‐1H‐pyrrole‐2,5‐dione

Conditions
Conditions Yield
With hydrogenchloride; tin(ll) chloride; In water; at 61 ℃; for 17h; Temperature; Inert atmosphere;
50.5%
With formic acid; triethylamine; In tetrahydrofuran; at 100 ℃; for 15h; chemoselective reaction; Inert atmosphere; Sealed tube;
90 %Chromat.
With [Mo3S4Cl3(4,4'-dinonyl-2,2'-bipyridine)3](PF6); hydrogen; In methanol; at 70 ℃; for 18h; under 15001.5 Torr; Autoclave;
70 %Chromat.

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    C40 H32 N4 O8

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    maleic anhydride

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29753-26-2 Downstream products

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    1430747-65-1

    N-(4-aminophenyl)imide of 1,4,5,6,7,7-hexachlorobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid

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